Data
Official data in SubjectManager for the following academic year: 2024-2025
Course director
Horváth Györgyi
associate professor,
Institute of Physiology
Number of hours/semester
Lectures: 28 hours
Practices: 0 hours
Seminars: 0 hours
Total of: 28 hours
Subject data
- Code of subject: OBI-006-E
- 2 Credit
- Biotechnology MSc
- Specialty in Pharmaceutical Biotechnology module
- autumn
haven't
Course headcount limitations
min. 1 people – max. 10 people
Topic
Without doubt there is an increasing demand for herbal medicinal products, nutraceuticals, and natural products for health care all over the world. Medicinal plants can produce several biologically active compounds during their primary and secondary metabolism. However, the production of these metabolites is critically affected by environmental factors and the cultivation of some medicinal plants is difficult. In some cases the active compound is produced in low quantities (e.g. taxol in Taxus brevifolia (0.015% dry weight) by the host plant. But there is possibility to change of genetic program of plants, plant cells and organs, and use their ability for technological purposes.
The aim of this course is to introduce the engineering of medicinal plants: prospects and limitations of medicinal plant biotechnology, the most important extraction methods and chromatographic techniques used in the research of medicinal plants, plant-associated microorganisms (endophytes) as a new source of bioactive natural products, in vitro culturing techniques of medicinal plants, breeding of medicinal plants, and the biosynthesis and classification of the most important plant secondary metabolites. Students should be able to apply the acquired knowledge in their job.
Lectures
- 1. Introduction. The engineering of medicinal plants: prospects and limitations of medicinal plant biotechnology - Horváth Györgyi
- 2. Introduction. The engineering of medicinal plants: prospects and limitations of medicinal plant biotechnology. - Horváth Györgyi
- 3. Metabolomics. Analytical methods used in biotechnology. - Horváth Györgyi
- 4. Metabolomics. Analytical methods used in biotechnology. - Horváth Györgyi
- 5. Plant-associated microorganisms (endophytes) as a new source of bioactive natural products. - Kocsis Marianna
- 6. Plant-associated microorganisms (endophytes) as a new source of bioactive natural products. - Kocsis Marianna
- 7. DNA profiling of plants. - Kocsis Marianna
- 8. DNA profiling of plants. - Kocsis Marianna
- 9. In vitro culturing techniques of medicinal plants. - Kocsis Marianna
- 10. In vitro culturing techniques of medicinal plants. - Kocsis Marianna
- 11. Breeding of medicinal plants. - Kocsis Marianna
- 12. Breeding of medicinal plants. - Kocsis Marianna
- 13. Biosynthesis and classification of terpenoids. - Horváth Györgyi
- 14. Biosynthesis and classification of terpenoids. - Horváth Györgyi
- 15. Special examples of medicinal plant biotechnology I.: Plant biochemistry and biotechnology of flavour compounds and essential oils. - Horváth Györgyi
- 16. Special examples of medicinal plant biotechnology I.: Plant biochemistry and biotechnology of flavour compounds and essential oils. - Horváth Györgyi
- 17. General features and classification of alkaloids. - Horváth Györgyi
- 18. General features and classification of alkaloids. - Horváth Györgyi
- 19. Special examples of medicinal plant biotechnology II.: Biotechnology and production of alkaloids. - Horváth Györgyi
- 20. Special examples of medicinal plant biotechnology II.: Biotechnology and production of alkaloids. - Horváth Györgyi
- 21. Special examples of medicinal plant biotechnology III.: Biotechnology and production of secondary metabolites of Ginkgo biloba. - Kocsis Marianna
- 22. Special examples of medicinal plant biotechnology III.: Biotechnology and production of secondary metabolites of Ginkgo biloba. - Kocsis Marianna
- 23. Special examples of medicinal plant biotechnology IV.: Biotechnology and production of artemisinin for malaria. - Kocsis Marianna
- 24. Special examples of medicinal plant biotechnology IV.: Biotechnology and production of artemisinin for malaria. - Kocsis Marianna
- 25. Special examples of medicinal plant biotechnology V.: Biotechnology and production of camptotechin. - Kocsis Marianna
- 26. Special examples of medicinal plant biotechnology V.: Biotechnology and production of camptotechin. - Kocsis Marianna
- 27. Test. - Horváth Györgyi
- 28. Test. - Horváth Györgyi
Practices
Seminars
Reading material
Obligatory literature
Literature developed by the Department
Notes
Recommended literature
Oliver Kayser, Wim Quax (2007): Medicinal Plant Biotechnology. From basic research to industrial applications. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Evans W.C.: Trease and Evans Pharmacognosy, Saunders, London, New York, 2000
Conditions for acceptance of the semester
Satisfactory fulfillment of 1 written test (min. 60%) based on the lectures. There is one possibility to repeat the exam.
Mid-term exams
Satisfactory fulfillment of 1 written test (min. 60%) based on the lectures. There is one possibility to repeat the exam.
Making up for missed classes
There is no possibility.
Exam topics/questions
The material of written test based on the lectures.
Examiners
- Horváth Györgyi